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ovarian reserve
Ovarian reserve is a term that is used to determine the capacity of the ovary to provide egg cells that are capable of fertilization resulting in a healthy and successful pregnancy. With advanced maternal age the number of egg cell that can be successfully recruited for a possible pregnancy declines, constituting a major factor in the inverse correlation between age and female fertility.
While there is no known method for assessing the ovarian reserve of individual women,〔Broekemans FJ et al. (1998) ''Ovarian reserve tests in infertility practice and normal fertile women.'' Maturitas. 30(2):205-14.〕 indirect determination of ovarian reserve is important in the treatment of infertility.〔Broekemans FJ et al. (2006) ''A systematic review of tests predicting ovarian reserve and IVF outcome.'' Hum Reprod Update. 12(6):685-718.〕
==Establishment==
The ovary is generally thought of as an egg bank from which the woman draws during her reproductive life. The human ovary contains a population of primordial follicles. At 18–22 weeks post-conception, the female ovary contains its peak number of follicles (about 300,000 in the average case, but individual peak populations range from 35,000 to 2.5 million〔Wallace WHB and Kelsey TW (2010) ''(Human Ovarian Reserve from Conception to the Menopause. )'' PLoS ONE 5(1):e8772. 〕).
The size of the initial ovarian reserve is strongly influenced by genetics.〔 Also, elevated androgen levels during prenatal development have an adverse effect on the early establishment of the ovarian reserve.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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